The health district covering the Fairfield and Liverpool areas have had 71 confirmed coronavirus cases.
The 71 confirmed cases represent a 1.04 per cent positivity rate after 6850 tests which is below the state average of 1.51 per cent.
It equates to 6.84 cases per 100,000 residents - which places SWSLHD tenth out of 15 health districts in NSW.
South West Sydney Local Health District is one of the the largest health districts in the state and includes Bankstown-Lidcombe Hospital, Bowral and District Hospital, Campbelltown and Camden Hospitals, Fairfield Hospital and Liverpool Hospital.
The data is based on the latest statistics as of 8pm on March 24.
The health district covering St George and Sutherland Shire has the highest number of confirmed coronavirus cases in Sydney.
A total of 292 cases have been recorded in the South Eastern Sydney Local Health District, which covers seven council areas from the CBD to Royal National Park.
Figures were also provided for each council area on the number of cases locally acquired where a contact has not been identified.
The number of such cases was in the 1-4 range for Liverpool. Fairfield didn't have a locally acquired COVID-19 case with an unknown source of infection.
The government is sending text messages telling Australians: "Stop the spread, stay 1.5m from others, follow rules on social gatherings, wash hands, stay home if sick".