A man with a shotgun stole money from a Westmead business on Thursday night.
Police said the man entered the bottle shop in Hawkesbury Road and demanded cash about 11pm.
An employee handed him some money and the robber fled, last seen heading south on Hawkesbury Road.
No one was hurt in the robbery.
Police want to speak to a man described as being of Caucasian appearance, about 180cm tall, with a thin build and wearing a black zip-up hooded-jacket, navy blue tracksuit pants and white Nike sneakers.
His face was covered with a blue and white chequered scarf.
Anyone with any information is urged to contact Parramatta detectives on 9633 0799 or 9688 8499 or Crime Stoppers on 1800 333 000.